Staff profile
Overview
https://apps.dur.ac.uk/biography/image/4758
William Earl
Research Postgraduate (PhD)
| Affiliation |
|---|
| Research Postgraduate (PhD) in the Department of Biosciences |
Biography
I am a PhD student in the department of Biosciences at Durham University. My research is focussed on the copper-dependent nitrite reductase, AniA, which is a metalloenzyme found in pathogenic bacteria Neisseria gonorrhoeae. Specifically, I am looking at the assembly of the enzyme and the insertion of copper, with a view to inhibit vilurence through blocking this process. I started my PhD in October 2024 after completing an MRes in the same lab also researching AniA. I completed a BSc in Natural Sciences at Durham University where I followed the Biology and Chemistry combined honours pathway.
Publications
Journal Article
- AccA from Neisseria gonorrhoeae provides a new framework for understanding periplasmic copper metallochaperonesFirth, S., Earl, W., Thaqi, D., Hong, Y., O’Hern, C., Luscombe, G., Ngu, D. H. Y., Luo, Z., Jobichen, C., Kobe, B., McEwan, A., & Djoko, K. (2026). AccA from Neisseria gonorrhoeae provides a new framework for understanding periplasmic copper metallochaperones. Chemical Science. Advance online publication. https://doi.org/10.1039/d5sc08738d